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H-Leu-Leu-OMe HBr
CAS No. 16689-14-8
H-Leu-Leu-OMe HBr( —— )
Catalog No. M34891 CAS No. 16689-14-8
H-Leu-Leu-OMe HBr (L-Leucyl-L-Leucine methyl ester HBr) is a dipeptide condensation product of L-Leucine methyl ester, a peptide that is toxic to natural killer T-cells and possesses immunosuppressive activity that abrogates all natural killer (NK) cell functions in mixed lymphocyte populations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | Get Quote |
|
| 10MG | 61 | Get Quote |
|
| 25MG | 113 | Get Quote |
|
| 50MG | 170 | Get Quote |
|
| 100MG | 245 | Get Quote |
|
| 500MG | 597 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameH-Leu-Leu-OMe HBr
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NoteResearch use only, not for human use.
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Brief DescriptionH-Leu-Leu-OMe HBr (L-Leucyl-L-Leucine methyl ester HBr) is a dipeptide condensation product of L-Leucine methyl ester, a peptide that is toxic to natural killer T-cells and possesses immunosuppressive activity that abrogates all natural killer (NK) cell functions in mixed lymphocyte populations.
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DescriptionL-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number16689-14-8
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Formula Weight339.27
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Molecular FormulaC13H27BrN2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (368.44 mM; Ultrasonic )H2O : 100 mg/mL (294.75 mM; Ultrasonic)
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SMILESBr.COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Thiele DL, et, al. The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes. J Immunol. 1986 Feb 1;136(3):1038-48.?
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